E-HPLC Tested Chondroitin

Testing method matters more than you think.

E-HPLC Tested Chondroitin

The testing method matters more than you think

The Industry Reality

Chondroitin is one of the most complex and frequently mischaracterized ingredients in the supplement market. Variability in raw materials, sourcing, and testing methods can lead to:

Inconsistent potency results
Misidentified material
Challenges in validating label claims

Why E-HPLC Matters

E-HPLC allows for:

True identity verification
Accurate differentiation of sulfated structures
Detection of non-specific or adulterated materials
Greater alignment with modern analytical expectations

Not All Testing Is Equal

There are multiple analytical approaches used in the industry:

CPC (Titration Method)

Measures the entire molecule as a whole
Commonly used for formulation calculations
Does not confirm molecular identity

Standard HPLC

Measures total polysaccharide content
Does not differentiate similar compounds
May overestimate true Chondroitin content

Enzymatic HPLC (E-HPLC)

Breaks Chondroitin into specific disaccharide components
Measures individual structural markers
Provides high specificity and accurate identification

Key Analytical Considerations

Advanced Chondroitin testing evaluates:
Disaccharide composition (4S / 6S ratios)
Identity confirmation prior to potency analysis
Acceptable variance between analytical methods
Additional purity indicators (sulfates, chlorides, electrophoretic profile)

Building Confidence Into Your Formula

When developing products containing Chondroitin:
Verify identity before potency
Understand which method is being used
Align testing methods with modern analytical standards
Work with suppliers who prioritize transparency and verification

“Testing methodologies referenced reflect established industry practices and publicly available compendial standards.”

A New Chapter For ASI Specialty Ingredients

Formerly ASI International, ASI Specialty Ingredients reflects the next evolution of a 30+ year multi-generational legacy built on trust and consistent values built to better support today’s pet nutrition market.

While our name is evolving, our commitment remains the same: helping manufacturers navigate sourcing challenges with reliable supply, strong supplier relationships and responsive support.

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Customized Sourcing

Solving sourcing challenges by connecting hard-to-find specialties with high-volume staples, tailored to your formulation, volume, & timing.

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Reliable Supply

Backed by a supplier network built over 30+ years and a robust national distribution footprint for rapid, reliable delivery.

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Confidence Through Compliance

We provide total peace of mind by meeting strict regulatory standards with seamless traceability and compliant documentation.

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Responsive Support

A solutions-oriented team of industry experts who understand your challenges, act fast and communicate clearly.

ASI Featured Ingredients

Amino Acids

Acetyl-L-Carnitine HCL
Agmatine Sulfate
Beta-Alanine
BCAA (Instant & Non Instant)
L-5-Hydroxytryptophan
L-Alanine
L-Arginine Base
L-Arginine HCL
L-Arginine-A-Ketoglutarate (2:1)
L-Arginine-Ethyl-Ester (1:1, 2:1)
L-Arginine-L-Pyroglutamate
L-Aspartic Acid
L-Carnitine Base
L-Carnitine Fumarate
L-Carnitine HCL
L-Carnitine Tartrate
L-Carnosine
L-Citrulline
L-Citrulline Malate (1:1)
L-Cysteine
L-Cysteine HCL Anhydrous
L-Cysteine HCL Monohydrate
L-Cystine
L-Glutamic Acid Base
L-Glutamine
L-Glutathione Reduced
L-Histidine Base
L-Histidine HCL
L-Isoleucine
L-Leucine
L-Lysine HCL
L-Methionine
L-Ornithine HCL
L-Ornithine-A-Ketoglutarate (1:1)
L-Ornithine-L-Aspartate
L-Phenylalanine

Botanicals, Fruits & Vegetables

Available in conventional, straight powders, extracts, and organic.

Acerola
Acai
Ashwaghanda
Bilberry
Blueberry
Butterbur Root
Camu Camu
Cat's Claw
Chuchuhuasi Bark
Citrus Aurantium
Cocoa Powder (Natural, Alkalized - High & Low Fat Contents)
Cranberry
Curcumin/Turmeric
Echinacea Herb
Epimedium
Garcinia Cambogia
Ginkgo Biloba
Goldenseal Root & Herb
Goji Berry
Grape Seed
Green Coffee Bean
Green Lipped Mussel
Green Tea
Guarana
Maca Root
Milk Thistle
Pumpkin
Purple Corn
Raspberry Ketone
Red Clover
Resveratrol
Sacha Inchi
Saw Palmetto
Schisandra
Sea Cucumber
St. John's Wort
Tribulus Terrestris

Specialty Ingredients

A-Ketoglutaric Acid
Alpha Lipoic Acid
Betaine Anhydrous
Betaine HCL
Bone Meal
Caffeine Anhydrous (Natural & Synthetic)
Chitosan
Chondroitin Sulfate Sodium*
Collagen*
Colostrum
DL-Methionine
DL-Phenylalanine
DMAE Bitartrate
GABA
Glucosamine HCL
Glucosamine Sulfate
Glycine
HMRLignan
Inositol Nicotinate
Melatonin
PABA
Shark Cartilage

*Available in Bovine, Chicken, Marine & Porcine.

Vitamins

D-Biotin
Niacin
Niacinamide
Vitamin A Acetate 500,000 IU/GM
Vitamin A Palmitate 250,000 IU/GM
Vitamin B-12 USP
Vitamin B-12 1% on DCP
Vitamin E 50%
Vitamin E Succinate 1185 IU/GM
Vitamin E Succinate 1210 IU/GM

E-HPLC Tested Chondroitin